Ulzero

Composition:

• Pantoprazole 40 mg (W.F.I.)

Description:

Ulzero Vial is a sterile injectable solution containing Pantoprazole, a proton pump inhibitor (PPI) that reduces stomach acid production. It is ideal for patients unable to take oral medications due to conditions like nausea, vomiting, or severe gastric issues.

Indications:

Ulzero Vial is used for the treatment of:

• Gastroesophageal Reflux Disease (GERD): Helps heal erosive esophagitis and reduces acid reflux symptoms.

• Peptic Ulcer Disease: Treats and prevents stomach and duodenal ulcers caused by excess acid.

• Zollinger-Ellison Syndrome: Manages excessive stomach acid production.

• H. pylori Eradication: Used in combination therapy to eliminate Helicobacter pylori infections.

• Prevention of Stress Ulcers: Helps critically ill patients avoid stress-related ulcers.

Benefits:

• Fast-acting relief for acid-related disorders.

• Effective healing of gastric and duodenal ulcers.

• Proven therapy for GERD and reflux symptoms.

• Reduces risk of gastrointestinal bleeding in critically ill patients.

Dosage and Administration:

• Usual Adult Dose: 40 mg (one vial) once daily via intravenous injection over 2-3 minutes.

• Treatment Duration:

  • GERD & ulcers: 7-14 days

  • Zollinger-Ellison syndrome: May require long-term treatment

  • H. pylori eradication: Used with antibiotics in a combination regimen

• Administration:

  • For IV use only

  • Administer slowly to avoid side effects

Storage Instructions:

• Store in a cool, dry place (below 25°C).

• Keep the vial in its original packaging to protect from light.

• Keep out of reach of children.

Precautions:

• Allergy: Avoid if allergic to Pantoprazole or other PPIs.

• Liver Disease: Use with caution in liver-impaired patients; dose adjustments may be needed.

• Long-term Use Risks: May increase the risk of bone fractures, vitamin B12 deficiency, and Clostridium difficile infections.

• Drug Interactions:

  • May interact with warfarin, methotrexate, and certain antifungal drugs.

  • Consult a doctor before use with other medications.

• Pregnancy & Lactation: Use only if necessary; discuss with a healthcare provider.

Side Effects:

• Common: Headache, nausea, diarrhea, dizziness, abdominal pain.

• Serious: Severe allergic reactions, liver dysfunction (jaundice), and low magnesium levels.

• Long-term Use Risks: May lead to bone fractures, kidney issues, and vitamin B12 deficiency.